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Vitamins C and E, and sulfasalazine can decrease sFlt-1 levels [203]

Treatment of HRS is best accomplished by increasing systemic vascular resistance, as with the vasopressin analog terlipressin, or by reducing portal venous pressure, which is most commonly accomplished with TIPS

Patients should maintain adequate hydration, especially if experiencing gastrointestinal side effects, to reduce the risk of acute kidney injury

Lifestyle interventions were the least effective treatment, the investigators found, producing a mean total body weight loss of 7.4% at the end of the treatment period, followed by a mean per-month weight regain of 0.14%, with participants reaching their pre-intervention weights within 4.1 years